Free American Society for Microbiology ABMM Exam Questions

Absolute Free ABMM Exam Practice for Comprehensive Preparation 

  • American Society for Microbiology ABMM Exam Questions
  • Provided By: American Society for Microbiology
  • Exam: American Board of Medical Microbiology (ABMM)
  • Certification: ASM-ABMM
  • Total Questions: 205
  • Updated On: Nov 24, 2025
  • Rated: 4.9 |
  • Online Users: 410
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  • Question 1
    • A patient develops a severe diarrheal illness after consuming raw seafood. Stool culture yields a Gramnegative, comma-shaped bacterium that is oxidase-positive and grows on thiosulfate-citrate-bile salts-sucrose (TCBS) agar, producing blue-green colonies. The MOST significant virulence factor contributing to the severe, cholera-like diarrhea caused by this organism is:


      Answer: C
  • Question 2
    • A clinical trial is evaluating the efficacy of a new antifungal agent against invasive aspergillosis. Serum galactomannan levels are being used as a biomarker to monitor the infection. A decrease in galactomannan levels during treatment would indicate: 


      Answer: B
  • Question 3
    • A clinical laboratory performs a cefoxitin disk diffusion test on a Staphylococcus aureus isolate from a wound culture. The zone of inhibition measures 18 mm. According to current CLSI M100 guidelines, how should this result be interpreted regarding oxacillin/methicillin susceptibility?


      Answer: B
  • Question 4
    • A patient with HIV infection and a CD4+ T-cell count below 50 cells/µL develops a progressive neurological illness characterized by confusion, motor deficits, and seizures. Brain MRI reveals multiple white matter lesions without mass effect. PCR of the CSF is positive for JC virus. Thepathogenesis of this condition, progressive multifocal leukoencephalopathy (PML), involves: 


      Answer: B
  • Question 5
    • A clinical isolate of Klebsiella pneumoniae from a patient with a refractory urinary tract infection exhibits resistance to carbapenems (imipenem, meropenem, ertapenem). PCR analysis reveals the presence of the blaKPC gene. Which of the following enzymatic mechanisms is responsible for this resistance?


      Answer: A
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